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What Is Actually HIFU and Who Is a Reasonable Choice With Prostate Cancer?

HIFU, or Intense Focused Ultrasound, is a noninvasive technique for treatment of localized prostate kind of cancer. HIFU focuses ultrasound energy and sound waves with a targeted area within the prostate resulting in rapid temperature increases and focal ablation with the treatment zone with great accuracy. In many instances, HIFU is performed while on an outpatient basis in one to 4 hours with regards to the size of the prostate. The greatest advantage of HIFU is definitely a low incontinence rate of below 2% along with a post-treatment erection dysfunction rate of 20 to 30%. The key to success with HIFU, however, is proper patient selection. Candidates include men with low- to intermediate-risk localized prostate type of cancer (i.e., no spread of cancer not in the prostate). These men might have clinical stage T1 or T2b disease (i.e., no palpable nodule or nodule confined one lobe in the prostate), Gleason score of seven or less (preferably not greater than Gleason Score 3+4=7), PSA degree of under 20, and a prostate level of 40 grams or fewer. Initial data to treat appropriately selected men with HIFU shows results comparable to other modalities regarding localized cancer control, biochemical recurrence, and disease-free survival. Additionally, reported incontinence and erectile dysfunction rates after HIFU are quite low at less that 2% and 20 to 30%, respectively.



Advantages of HIFU as a method of treating select men with cancer of the prostate include a non-surgical, minimally invasive technique requiring no a hospital stay. Additionally, the prostate kind of cancer tissue is destroyed with no radiation exposure. HIFU is repeatable should re-treatment become necessary later on. Additionally, HIFU may be used to treat recurrent prostate type of cancer which was initially treated by other means, for example radiation or proton therapy. Another impressive putting on HIFU to treat localized prostate type of cancer is in emerging successes with focal therapy of prostate cancer. Over these select cases, studies can be performed to be sure a low-volume of cancer of the prostate restricted to one lobe or even a specific focal site inside prostate. The involved lobe or perhaps the specific site with the patient's prostate type of cancer would then be focally treated. Candidates for focal HIFU include men with low-volume (under or add up to 3 cores positive for cancer, no core with more than 50% positive), Gleason Score of 6 or fewer, plus a PSA of less than 10. These men would undergo "template" or "saturation" biopsies with greater to 24 cores evaluated. Research studies taking a look at focal therapy of prostate type of cancer in very select men with low-volume disease are emerging and early results look promising although no long term information is yet available. Early results in some studies show approximately 90% recurrence free survival following focal therapy in observed at close range men. Incontinence rates following focal HIFU were 0 to 1% and male impotence rates below 5% in a study taking a look at results at three and six months following treatment.

HIFU is really a noninvasive treatment choice for men with low- to intermediate-risk prostate kind of cancer. The true secret to its success like all selections for treatment is based on appropriate candidate selection. HIFU is performed internationally which is currently undergoing clinical trials for FDA approval in the US. American urologists are been trained in performing HIFU and assist American teams internationally as a way to offer botox injections to appropriately selected patients enthusiastic about HIFU as a means of treating their prostate kind of cancer. As always, be sure to discuss all options along with your urologist including the risks, benefits and options to each prior to the best decision regarding treatments for your prostate cancer. Maintain open and honest discussions along with your doctor when it comes to these options because the key to your success is finding the treatment you like plus your particular cancer the very best.

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